Coenzyme Q-10-HUZHOU SHENGMA BIOCHEM CO., LTD.

Coenzyme Q-10

Update: 2015/4/16 View:

Brand:
Type:

Introduction

EP/USP/JP

Coenzyme Q10

Description:

Coenzyme Q10 (CoQ10) is (produced by the human body) and is necessary for basic functioning of cells. CoQ10 levels decrease with age. Some prescription drugs may also lower CoQ10 levels. Taking CoQ10 supplements can increase levels of CoQ10 in the body. However, it is not clear that replacing "low CoQ10" is beneficial. CoQ10 has been used, recommended, or studied for numerous conditions and remains controversial as a treatment in many areas.

Claims:

Uses These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.	Grade^*
High blood pressure	B
Alzheimer's disease, Angina (exercised-induced), Anthrocycline chemotherapy toxicity	C
Breast cancer, HIV/AIDS, Decreased sperm movement, Friedreich's ataxia	C
Chronic lung disease, Kidney failure (chronic)	C
Heart attack, Heart failure & cardiomyopathy, Heart protection during CABG surgery	C
Mitochondrial disease & Kearns-Sayre syndrome, Muscular dystrophy, Periodontitis (gum disease)	C
Diabetes, Huntington's disease	D
*Key to grades: A: Strong scientific evidence for this use; B: Good scientific evidence for this use; C: Unclear scientific evidence for this use; D: Fair scientific evidence against this use; F: Strong scientific evidence against this use

Safety:

No reported allergy associated with Coenzyme Q10 supplements, although rash and itching have been reported rarely. Stop use two weeks before surgery/dental/diagnostic procedures with bleeding risk and do not use immediately after these procedures. Use caution if history of blood clots, diabetes, high blood pressure, heart attack, or stroke, or with anticoagulants (blood thinners) or antiplatelet drugs (like aspirin, warfarin, clopidogrel (like Plavix®), blood pressure, blood sugar, cholesterol or thyroid drugs. Avoid if pregnant or breastfeeding.

Possible side effects:

Bleeding, blood clots, breathing problems, bruising, dizziness, fatigue, flu-like symptoms, headache, irritability, itching, liver enzymes changes, sensitivity to light, skin rash, sleep changes, stomach upset, thyroid hormones changes.

Possible interactions:

Anticoagulants (blood thinners) or antiplatelet drugs like (aspirin, warfarin, clopidogrel (like Plavix®)), beta blockers, clonidine, methyldopa, hydralazine, antidepressants, antipsychotics, blood pressure drugs, blood sugar medications (insulin, metformin (Glucophage®)), cholesterol-lowering drugs (statins), some diuretics (water pills), ginkgo, garlic, horsetail, red yeast, vitamin E, vitamin K and other herbs or supplements with similar effects.

Dosing:

Adults (18 years and older):

Alzheimer's disease: 120mg has been taken by mouth three times daily, or 60mg daily with 150mg of iron and 180mg of vitamin B6 has been taken.

Heart failure/cardiomyopathy: 100-600mg, or 2mg (per kilogram of body weight) has been taken by mouth daily.

High blood pressure: 75-360mg has been taken by mouth daily.

Muscular dystrophies: 100mg by mouth in divided doses has been suggested.

Parkinson's disease: 300-1200mg has been taken daily.

Children (younger than 18 years):

For reducing heart damage by chemotherapy drugs, 100mg taken by mouth twice daily has been used.

For mitral valve prolapse (heart murmur) 3.0-3.4mg/kg has been taken by mouth daily.

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